Endocrine Abstracts

Introduction: Metastases in the pituitary gland are an uncommon presentation of carcinomas, lung and breast being the most common sites of the primary tumor. The most frequent clinical manifestations are diabetes insipidus, visual disturbances, cranial nerve paralysis and hypopituitarism.Case report: We report the case of a 64 years old man, smoker, with no chronic illness, with one year history of headache, and more recent asthenia, weight loss, poliuri...

Introduction: Hypothalamic obesity is defined as a syndrome of intractable weight gain as a result of hypothalamic lesions. Craniopharyngioma is responsible for more than half of the cases of hypothalamic obesity, but other pathologies can be implied. The syndrome can occur due to the tumour itself or its treatment (surgery or radiotherapy). Metformin is an antidiabetic drug that has also been used to treat nondiabetic obese patients, as it has been demonstrated to promote wei...

Introduction: Primary hyperparathyroidism (PHPT) is a well-known risk factor for urolithiasis and nephrocalcinosis, wich are now less commonly reported due to an early detection of hypercalcemia by routine measurement of serum calcium. PHPT is most commonly caused by a single adenoma of the parathyroid gland. The incidence of multiglandular disease (MGD) range from 2.4–34%. In case of large tumor differential diagnosis is necessary to rule out malignancy.<p class="abs...